Topic hub

Mitochondria

Almost everything you feel as energy is made in the mitochondria. The panel is clearest about the unglamorous levers: easy aerobic work, real daylight, a little deliberate cold.

3 verdicts · updated monthly

The verdicts in this hub

Answer first, label earned, receipt attached.

A ten minute walk after meals

Ten easy minutes after eating blunt the glucose spike better than most supplements.

Recommended

“The cheapest glucose control we know is a walk that starts within fifteen minutes of your last bite.”

a metabolic PhD · podcast episode · 00:37:12

CoQ10 alongside statins

If statins bring muscle aches, CoQ10 is a sensible, low-risk experiment.

Worth exploring

“Statins lower the same pathway that makes CoQ10, so the logic of replacing it is sound. The trials are mixed, but for aching muscles it is a low-risk conversation to have.”

a cardiologist · source video · 00:33:02

Methylene blue in low doses

Our sources are genuinely split: an intriguing electron shuttle, or a drug that deserves more caution.

Genuinely contested

“The mechanism is genuinely elegant: it can accept and donate electrons inside the chain. Elegant mechanisms are not the same thing as outcomes in humans.”

a mitochondrial researcher · lecture · 01:08:26

The liveliest disagreement here

On methylene blue in low doses, our sources are genuinely split.

One side

“The mechanism is genuinely elegant: it can accept and donate electrons inside the chain. Elegant mechanisms are not the same thing as outcomes in humans.”

a mitochondrial researcher · lecture · 01:08:26

The other

“This is a prescription-grade compound with serious interactions, especially with common antidepressants. It should not be a casual purchase.”

a pharmacologist PhD · podcast episode · 00:46:13

Still filling in

Our sources have not said much yet about urolithin A, NAD precursors, or hyperbaric oxygen. As new talks and posts arrive each month, this hub will fill in.